Prof Mike Cousin has been awarded an Investigator Award in Science by the Wellcome Trust. This is a 5 year award totalling £1.78 million which will determine the role of activity-dependent bulk endocytosis in mammalian physiology at the molecular, synaptic, circuit and behavioural level.
The Seed Award received by the Wellcome Trust will enable Dr Carole Torsney and her team to utilise neuronal activity marker transgenics to gain direct access to spinal allodynia circuitry in a clinically relevant chronic pain model. By gaining morphological, electrophysiological and genetic ‘access’ to this circuitry they aim to identify the neuronal subpopulations, interconnections and mediators that communicate allodynia. This is a necessary prerequisite to developing therapeutics to limit their activity and treat this debilitating symptom.
Dr Nathalie Rochefort secured an enhancement fund for her project on 'Large population 2-photon imaging and targeted optogenetics in the mouse primary visual cortex'. This funding will help, developing the imaging technique Nathalie has implemented in CIP during the last 2 years. Nathale and her team are using this approach to investigate the Neuronal circuits and synaptic mechanisms of experience-dependent plasticity.
The Wellcome Trust
Prof Mike Cousin's research profile
Dr Carole Torsney's research profile
Dr Nathalie Rochefort's research profile