Highly differentiated tissues, such as the central nervous system, are constantly exposed to a variety of challenges.
These include mechanical injury, degeneration, inflammation, and uncontrolled growth. In this theme, groups cooperate to discover the cellular and molecular mechanisms that underpin cell and tissue differentiation, resilience to injury, and repair processes.
We employ a variety of cellular models, model organisms, and screening approaches. This maximises synergy between groups in making fundamental discoveries and expediting translation of these to clinical research.
Theme Lead: Dr Thomas Becker
| Name | Research interest |
|---|---|
| Becker, Catherina | Development and regeneration of the zebrafish nervous system |
| Becker, Thomas | Development and regeneration of the zebrafish nervous system |
| Brophy, Peter | Molecular and cell biology of axon-glia interactions in health and disease |
| Fowler, Jill | Mechanisms of neurodegeneration in stroke and dementia |
| Hall, Andrew | Chondrocytes, cartilage and osteoarthritis |
| Paxton, Jennifer | Musculoskeletal tissue engineering |
| Ribchester, Richard | Development, plasticity, degeneration, and regeneration of neuromuscular connections. |
| Sieger, Dirk | Microglia-tumour interactions |
| Torsney, Carole | Somatosensory plasticity |
| Wyllie, David | Physiology and pharmacology of ion channels |