The research theme is investigating the function and regulation of organs and tissue. Members of this grouping are concerned with the regulation of function of organs and tissue, including regulation of the brain, pituitary, heart and kidney by neural, endocrine, paracrine and autocrine signalling mechanisms.Theme Lead: Prof Mike LudwigNameResearch interestBrunton, PaulaStress PhysiologyDenholm, BarryOrgan development and physiologyDuncan, PeterCorticotroph cells and the stress responseEvans, MarkCalcium signalling & hypoxia-response couplingFleetwood-Walker, SusanMolecular mechanisms of pain and analgesiaHardingham, GilesProtective & degenerative signalling in the CNSKarnani, MaheshNeural circuits of drive.Le Tissier, PaulRegulation of the anterior pituitary glandLivingstone, DawnSteroid hormone signallingLudwig, MikeNeuropeptides and their effects on behaviourMenzies, JohnAppetite control and food choiceMitchell, RoryReceptor-mediated signal transductionRomano, NicolaSingle cell information processing in the pituitaryShipston, MikeIon channel physiology This article was published on Tuesday 27 October 2026