The research theme is investigating developmental mechanisms at molecular, genetic and cellular level. Genes and Development is a research grouping of biomedical scientists investigating the molecular, genetic and cellular developmental mechanisms in a wide range of tissues and systems, including kidneys and nephrocytes, neural development, and male and female reproductive systems.Genes and Development have now been meeting for around twenty years, holding research seminars, meetings of PIs and retreats.Theme Lead: NameResearch interestCobb, Stuart Novel therapies for neurodevelopmental disordersDavies, JamieOrganogenesis, synthetic biology, databasesDenholm, BarryOrgan development and physiologyDoitsidou, MariaDegeneration of dopaminergic neuronsGillingwater, TomNew therapies for neurodegenerative diseasesHardingham, GilesProtective & degenerative signalling in the CNSHasel, PhilipAstrocyte subtypes at brain bordersLe Tissier, PaulRegulation of the anterior pituitary glandLyons, DavidMechanisms of myelinated axon formation, function and repairO'Hara, LauraSex steroid receptors in the hypothalamus and pituitaryPratt, TomRoles of carbohydrates in the developing brainRomano, NicolaSingle cell information processing in the pituitaryRosario, RoseanneOvarian biology and female fertilitySibley, ChrisRegulation of RNA metabolism in neurological diseaseSimmen, MartinComputational modelling of nucleosome positionsTelfer, EvelynFollicle and oocyte developmentTheil, ThomasPatterning and axon pathfinding in the forebrainvan den Driesche, SanderMale reproductive health and disordersZoupi, LidaAxon-myelin interactions in health and neurodevelopmental disorders This article was published on Tuesday 27 October 2026