Past seminars and events in 2022/23 at the Centre for Discovery Brain Sciences. ‘Early postnatal development of neocortex-wide activity patterns in GABAergic and pyramidal neurons' Dr Michael Ashby, Senior Lecturer, School of Physiology, Pharmacology & Neuroscience, University of Bristol Thursday 14th March 2024, 13:00, HRB Lecture Theatre (Hybrid) Host: Dr Susana Ribeiro dos Louros 'The Development History of the Molecular Synaptic Code' Dr Fekrije Selimi, CIRB, Collège de France, Paris Tuesday 12th March 2024, 13:00, Auditorium A, Chancellors Building (Hybrid) Host: Prof Seth Grant 'Mechanisms of musculoskeletal pain' Prof Shafaq Sikandar, Professor of Sensory Neurophysiology, Experimental Medicine and Rheumatology, Queen Mary University of London Thursday 29th February 2024, 13:00, HRB Lecture Theatre (Hybrid) Host: Dr Carole Torsney Prof Masahisa katsuno: 'Prodromal cohort of Lewy body disease for development of biomarkers and preventive therapies' + Dr Yohei Iguchi: 'IκB kinase beta as a novel therapeutic target for ALS' Prof Masahisa katsuno, Department of Neurology, Nagoya University, Japan + Dr Yohei Iguchi Department of Neurology, Nagoya University, Japan Monday 19th February 2024, 13:00, Auditorium B, Chancellors Building (Hybrid) Hosts: Dr Bhuvaneish Selvaraj and Prof Tilo Kunath 'The interaction of learning with innate behaviour and its effect on evolution' Paul Conway, PhD Student, Ryan Lab, Trinity College Dublin Thursday 15th February 2024, 13:00, HRB Lecture Theatre (Hybrid) Host: Dr Francesco Gobbo 'Investigating mechanisms by which oligodendrocyte precursor cells govern the size of retinal ganglion cell in the Zebrafish visual system' Emma Dumble, ECR Czopka lab, University of Edinburgh Monday 5th February 2024, 13:00, Auditorium A, Chancellors Building (Hybrid) Host: Prof Tim Czopka 'The energetics of epilepsy: feeding the good and bad energy' Dr Felix Chan, Lecturer, Aston Pharmacy School, Aston University, Birmingham Thursday 1st February 2024, 13:00, HRB Lecture Theatre (Hybrid) Host: Prof Mike Cousin 'Prominent in vivo influence of single interneurons in the developing and adult cortex' Dr Rosa Cossart, Director of the Institute of Mediterranean Neurobiology (INMED), affiliated to INSERM and Aix-Marseille University Thursday 14th December 2023, 13:00, HRB Lecture Theatre (Hybrid) Host: Prof Nathalie Rochefort 'Identifying astrocyte endfoot functions using proteomics' Dr Steve Hill, Postdoctoral research fellow, DRI, Centre for Discovery Brain Sciences Monday 4th December, 13:00, Auditorium B, Chancellors Building (Hybrid) Host: Dr Blanca Díaz Castro 'TREM2 confers resilience against vascular cognitive impairment' Dr Stefan Szymkowiak, Postdoctoral research fellow, Centre for Discovery Brain Sciences Monday 20th November, 13:00, Undergraduate Medical Teaching Room (GU318), Chancellors Building (Hybrid) Host: Dr Barry McColl ‘Mapping the human brain feeding circuitry using single cell and spatial approaches’ Prof Giles Yeo, Professor of Molecular Neuroendocrinology at the MRC Metabolic Diseases Unit, University of Cambridge Thursday 16th November 2023, 13:00, HRB Lecture Theatre (Hybrid) Host: Prof Mike Ludwig 2023 Mary Pickford Lecture + Alison Douglas Prize Giving (best PhD thesis) 'The cognitive map: from neurons to architecture' Prof Kate Jeffery, Head of School Psychology & Neuroscience, University of Glasgow Thursday 9th November 2023, 12.30, HRB Lecture Theatre (Hybrid) Host: Prof David Wyllie 'Analysing the impact of extracellular vesicles on the establishment of glioma promoting functions in microglia Dr Julie Mazzolini, Postdoctoral Researcher, Centre for Discovery Brain Sciences Monday 6th November 2023, 13:00, Auditorium B, Chancellors Building (Hybrid) Host: Dr Jian Gan Feldberg Foundation Lecture with Prof Jan Born ‘Sleep – a brain state serving memory formation’ Prof Jan Born, Director of the Department of Medical Psychology and Behavioral Neurobiology University of Tübingen, Germany, Feldberg Foundation (German) prize winner 2023 Thursday 2nd November 2023, 13:00, HRB Lecture Theatre (Hybrid) Host: Prof Richard Morris 'Deconstructing the cerebellar modules to understand their functions' Dr Zhenyu Gao, Associate Professor, Dept. of Neuroscience, Erasmus MC, Rotterdam Monday 23rd October, 13:00, Auditorium B, Chancellors Building (Hybrid) Host: Prof Dies Meijer 'Protective mechanisms of synaptic stimulation in Alzheimer’s disease and tauopathies' Dr Davide Tampellini, Senior Researcher Institut Professeur Baulieu and Neuroscience, Inserm, Université Paris-Saclay, France Thursday 19th October 2023, 13:00, HRB Lecture Theatre (Hybrid) Host: Prof Tara Spires-Jones ‘AMPA receptor nanoscale organization and dynamics tune short and long term synaptic plasticity’ Dr. Daniel Choquet, Unity Director/Team leader, Bordeaux Neurocampus, Bordeaux University, France Monday 9th October 2023, 13:00, Auditorium B, Chancellors Building (Hybrid) Host: Dr Patricio Opazo 'Inhibitory top-down projections from zona incerta mediate neocortical memory’ Dr Anna Schroeder, Institute of Physiology, University of Freiburg, Germany Thursday 5th October 2023, 13:00, HRB Lecture Theatre (Hybrid) Host: Dr. Leena Williams 'Astrocytes dynamics in APP/PS1 mice-experience in a pilot grant application’ Dr Juraj Koudelka, Research Fellow/Imaging Lead, DRI University of Edinburgh Monday 25th September 2023, 13:00, Auditorium A, Shirley Hall (GU108), Chancellors Building (Hybrid) Host: Dr Jian Gan 'Deciphering the neural circuits that underlie auditory hallucinations' Dr Stanislav Zakharenko, St Jude Children's Research Hospital, Memphis, TN Tuesday 19th September 2023, 16:00, SIDB Boardroom, G31, HRB link Building Host: Prof Matt Nolan 'Origins of speed control in the spinal cord' Dr David McLean, Associate Professor, Department of Neurobiology, Northwestern University, USA Monday 11th September 2023, 13:00, HRB Lecture Theatre (Hybrid) Host: Prof David Lyons 'Learning a cognitive map' Dr Adrien Peyrache, Department of Neurology and Neurosurgery, McGill University, Montreal Thursday 29th June 2023, 13:00, HRB lecture theatre (Hybrid) Host: Dr Adrian Duszkiewicz 'Synaptic and circuit basis of distinct memory formation in the hippocampus’ Dr Christoph Schmidt-Hieber, neural circuits for spatial navigation and memory, Institut Pasteur, Paris Thursday 15th June 2023, 13:00, HRB lecture theatre (Hybrid) Host: Dr Tom Flossmann 'State-dependent patterns of neuromodulatory signaling in the cortex’ Dr Jessica Cardin, Associate Professor Tenure; Deputy Chair, Neuroscience, Yale School of Medicine Thursday 1st June 2023, 13:00, (Virtual) Host: Prof Nathalie Rochefort ‘Midbrain circuits for flexible instinctive behaviours' Dr Vanessa Stempel, Research Group Leader, Max Planck Institute for Brain Research, Germany Thursday 25th May 2023, 13:00, HRB lecture theatre (Hybrid) Host: Dr Sam Booker ‘Engineering neuroscience with microfluidics: complex in vitro models made easy’ Dr Michele Zagnoni, Reader, Electronic and Electrical Engineering, University of Strathclyde Monday 15th May 2023, 13:00, CB (Hybrid) Host: Prof David Lyons 'Visual Cortex and Tauopathy: insights into network level dysfunction in disease' Dr Fabio Ribeiro Rodriguez, Department of Experimental Psychology, UCL Thursday 11th May 2023, 13:00, HRB lecture theatre (Hybrid) Host: Prof Tara Spires-Jones ‘Spatial assessment of ALS’ Prof Hemali Phatnani, Director of the Center for Genomics of Neurodegenerative Disease, NYC + Assistant Professor of Neurological Sciences in the Department of Neurology, Columbia University Monday 24th April 2023, 13:00, Auditorium B, Chancellors Building (Hybrid) Host: Profs Colin Smith + Seth Grant 'Neural mechanisms for emotional behavior and decision making' Dr Andrew Macaskill, Principal Research Fellow, Neuro, Physiology & Pharmacology, UCL Thursday 13th April 2023, 13:00, HRB lecture theatre (Hybrid) Host: Prof Matt Nolan 'Impact of transposable elements in neurodevelopment and neurodegeneration' Dr Marco Trizzino, Senior Lecturer in Developmental Genomics, Imperial College London Monday 3rd April 2023, 13:00 (Virtual) Host: Dr Kathryn Bowles 'The neurobiology of individuality' Prof Gerd Kemperman, Adult neurogenesis, speaker and research group leader - DZNE, Dresden Tuesday 21st March 2023, 13:00, Undergraduate Medical Teaching Room (GU318), BioQuarter (Hybrid) Hosts: Prof Seth Grant 'A gut sense' Dr Melanie (Maya) Kaelberer, sensory neuro-gastroenterologist, Duke University, Durham, NC Thursday 16th March 2023, 13:00, HRB lecture theatre (Hybrid) Host: Dr Ann Clemens ***CANCELLED*** 'Targeting Foam Cells (Macrophages) to Improve Stroke Recovery' Dr Kristian Doyle, Associate Professor of Immunobiology and Neurology, University of Arizona Monday 6th March 2023, 13:00, lecture theatre B, Chancellors Building (Hybrid) Host: Dr Barry McColl ‘Cortical wiring by synapse type-specific control of local protein synthesis’ Dr Clémence Bernard, Research Associate, Kings College London Thursday 2nd March 2023, 13:00, HRB lecture theatre (Hybrid) Host: Dr Lida Zoupi 'Directed evolution of molecular tools for the mapping and manipulation of active neuronal circuits' Dr Mateo Sanchez, Postdoctoral Fellow (Bioengineering), Imperial College London Thursday 2nd February, 2023 13:00, HRB lecture theatre (Hybrid) Host: Dr Francesco Gobbo 'Mechanisms driving joint pain' Prof Ewan St John Smith, Corpus Christi College, Cambridge Thursday 19th January 2023, 13:00, HRB lecture theatre (Hybrid) Host: Dr Carole Torsney 'Neuron Differentiation: From Chromatin to Connectivity’ Dr Adrian Moore, Riken Centre for Brain Science, Hirosawa Wako City, Japan Monday 9th January 2023, 13:00, QMRI - Wellcome Auditorium (E1.01), (Hybrid) Host: Prof Seth Grant 'Astrocytes in tauopathies' Professor Wendy Noble, Professor in Molecular Neurodegeneration, King’s College London Monday 12th December 2022, 13:00, Undergraduate Teaching Room, Chancellors Building (Hybrid) Host: Prof Karen Horsburgh ***Postponed*** Prof Megan Carey, Champalimaud Center for the Unknown, Lisbon Thursday 1st December, 13:00, HRB lecture theatre Hosts: Prof James Boardman & Prof Ian Duguid 'Putting a spin on developmental biology and flies to battle neurodegeneration' Professor Andreas Prokop, Division of Molecular & Cellular Function, University of Manchester Thursday 17th November, 13:00, HRB lecture theatre Host: Prof Jamie Davies ***This event is sponsored by BSDB - British Society for Developmental Biology*** 2022 Mary Pickford Lecture/Alison Douglas Prize (best PhD thesis) With Prof Maria Fitzgerald - 'Pain and the developing brain' Professor Maria Fitzgerald, Professor of Developmental Neurobiology, UCL Thursday 10th November, 13:00, Anatomy Lecture Theatre Host: Prof David Wyllie 'Fire-together, wire together: The role of human hippocampal oscillations and spike-timing dependent plasticity in shaping episodic memory codes' Professor Simon Hanslmayr, Centre for Cognitive Neuroimaging, University of Glasgow Thursday 3rd November, 13:00, HRB lecture theatre Host: Prof Matt Nolan 'Neural circuit mechanisms for episodic memory’ Dr Takashi Kitamura, Assistant Professor, Department of Psychiatry and Department of Neuroscience, University of Texas Southwestern Medical Center, USA Monday 17th October, 15:00, (virtual) Host: Dr Szu-Han Wang 'The molecular nanoarchitecture that controls synaptic transmission' Professor Thomas Blanpied, University of Maryland, Baltimore Monday 3rd October, 14:00, (virtual) Host: Prof Seth Grant 'Neurosteroid based therapies for improving outcome following compromised pregnancies' Professor Jon Hirst, University of Newcastle Thursday 29th September, 13:00, HRB lecture theatre (Hybrid) Host: Dr Paula Brunton 'Perivascular macrophages and SPP1 imprint microglial phagocytic states in Alzheimer’s disease models' Dr Sebastiaan (Seppe) De Schepper, Postdoctoral fellow, UK Dementia Research Institute at University College London Wednesday 28th September, 15:00, Lecture Theatre B, Chancellors Building Host: The Microglia Club 'Expression of ApoE2 can protect against plaque deposition, neuroinflammation, and neurodegeneration despite the presence of ApoE4' Dr Rosie Jackson, Massachusetts General Hospital, Boston, Massachusetts, United States Monday 26th September, 13:00, Gaddum lecture theatre Host: Prof Tara Spires-Jones 'Cognitive Resilience' Dr Thomas Montine, MD, PhD, Medicine Professor Of Pathology, Stanford University, CA ***Cancelled*** Thursday 22nd September, 13:00, HRB lecture theatre Host: Prof Tara Spires-Jones 'Matrix Resurrections: Novel Therapeutic Targets for Cerebrovascular Disease and COVID-19' Professor Greg Bix, Director, Clinical Neuroscience Research Center, Tulane University, USA Tuesday 13th September 2022, 13:00, LTB, Chancellors Building. Host: Prof Karen Horsburgh 'Gene-environment interactions modulating brain function within and between generations' Professor Tony Hannon, Florey Institute of Neuroscience and Mental Health, Victoria, Australia Monday 13th June, 13:00, HRB lecture theatre (Hybrid) Host: Prof Tara Spires-Jones 'Translational behavioral studies reveal the potential for cannabis to treat bipolar disorder' Professor Jared Young, University of California, San Diego | UCSD · Department of Psychiatry Monday 6th June 2022, 13:00, Lecture Theatre B, Chancellors Building (Hybrid) Host: Dr Jill Fowler 'Cellular and Molecular Mechanisms of Cortical Interneuron Development' Dr Myrto Denaxa, Alexander Fleming Biomedical Sciences Research Center, Greece. Thursday 19th May 2022, 13:00 (virtual) Host: Dr Lida Zoupi The Physiological Society Members Roadshow plaque unveiling to Edward Sharpey-Schafer Dr Kate Ellacott, Associate Professor in Biomedical Neuroscience, University of Exeter Tuesday 10th May 2022, 2:00pm, Anatomy, Teviot Host: Prof David Wyllie 'Structural constraints of neuron-astrocyte interactions at glutamatergic synapses' Professor Christian Henneberger, Institute of Cellular Neurosciences, Medical Faculty, University of Bonn Thursday 5th May 2022, 13:00 (virtual) Host: Prof Mark Evans 'Intrinsic synaptic dynamics and why they matter' Professor Noam Ziv, Technion-Israel Institute of Technology Monday 25th April 2022, 13:00 (virtual) Host: Prof Seth Grant 'The role of glia-neuron interactions in brain excitability and seizures' Professor Emre Yaksi, Kavli Institute for Systems Neuroscience, Norway Monday 11th April 2022, 13:00 Host: Dr Tim Czopka 'Vision in Action: Visual processing in active behaviours' Dr Aman Saleem, Part of PALS Experimental Psychology, University College London Thursday 7th April 2022, HRB lecture theatre, 14:00 Host: Prof Matt Nolan 'What does the retrosplenial cortex do? Visual responses and visuospatial memory engrams' Prof Frank Sengpiel, Head of Neuroscience Division, Cardiff University Monday 28th March 2022, 13:00 Host: Prof Seth Grant 'All-optical interrogation of the hippocampal role in episodic memory formation, consolidation and retrieval' Dr Nick Robinson, Research Associate, Wolfson Inst for Biomedical Research, UCL Thursday 10th March 2022, 13:00 (virtual) Host: Dr Emma Wood 'Idling brain: from memory engram to behavior' Prof Kaoru Inokuchi, Department of Biochemistry, University of Toyama, Japan Monday 7th March 2022, 11:00 please note unusual start time Host: Dr Szu-Han Wang 'Explorations in Ca2+ imaging of neural activity in freely moving rats: social cells, place cells and goal cells' Professor Richard Morris, FRS, Dr Francesco Gobbo + Rufus Mitchell-Hegg Thursday 3rd March, 13:00 Host: Dr Nicola Romano + Dr Lida Zoupi 'Regional differences in neurovascular coupling and implications for disease' Dr Catherine Hall, School of Psychology, University of Sussex Monday 28th February 2022, 13:00 Host: Prof Karen Horsburgh 'Inhibitory Microcircuits for Associative Learning' Dr Sabine Krabbe, Group Leader, DZNE, Bonn Thursday 24th February 2022, 13:00 Host: Prof Ian Duguid 'Non-productive angiogenesis in Alzheimer’s disease, a glimpse on how AD compromises non-neuronal cells' Dr Alberto Pascual, The Neuroscience Institute at Seville (IBiS) Monday 14th February 2022, 13:00 Host: Dr Blanca Diaz-Castro 'Subcortical Networks to Control Seizures' Dr Patrick Forcelli, Associate Professor and Vice-Chair, Pharmacology & Physiology, Neuroscience, Georgetown University Thursday 10th February 2022, 15:00 Host: Dr Alfredo Gonzalez-Sulser 'Oligodendrocyte progenitors alter the extracellular matrix to control differentiation and morphogenesis' Prof Dwight Bergles, John Hopkins Medicine, USA Monday 31st January 2022, 13:00 Host: Prof David Lyons More than bystanders, learning how microglia eliminate synapses in the Alzheimer brain Dr Soyon Hong, UK Dementia Research Institute; UCL Monday 17th January 2022, 13:00 Host: Prof Anna Williams 'Role of tanycyte shuttles and networks in the control of glucose and energy homeostasis' Dr Vincent Prevot, French Institute of Health and Medical Research | Inserm · Development and PLasticity of the Postnatal Brain Thursday 13th January 2022, 13:00 Host: Dr Nicola Romano