Well done to Robin Beaven, Luigi Zechini and Sybille Koehler (Denholm lab) on their latest publications. Robin Beaven discovers a novel developmental mechanism that patterns the proximo-distal axis of the fly renal tubule: Early patterning followed by tissue growth establishes distal identity in Drosophila Malpighian tubules Published in Frontiers in Cell and Developmental Biology https://doi.org/10.3389/fcell.2022.947376 Luigi Zechini et al show the mechanically-activated ion channel, Piezo, is an important component of the fly heart’s ability to adapt to mechanical force: Piezo buffers mechanical stress via modulation of intracellular Ca2+ handling in the Drosophila heart Published in Frontiers in Physiology https://doi.org/10.3389/fphys.2022.1003999 Sybille Koehler finds the mechanosensor, Cheerio, provides a key protective role in fly nephrocytes (insect filtration cells that resemble kidney podocytes) depleted of their filtration apparatus. A protective role for Drosophila Filamin in nephrocytes via Yorkie mediated hypertrophy Published in Life Science Alliance DOI: 10.26508/lsa.202101281 This article was published on 2022-10-17
