Vinothini Prabhakaran

Personal Profile

• 2021 - present: PhD, Anatomy - Biomedical Sciences, University of Edinburgh, UK
• 2019 - 2020: Junior Research Fellow, Indian Veterinary Research Institute, Bareilly, India.
• 2018 - 2019: Assistant Professor, Rajiv Gandhi Institute of Veterinary Education & Research, Puducherry, India.
• 2016 - 2018: Masters in Veterinary Pharmacology and Toxicology, Tanuvas, India.
• 2015 - 2016: Pet clinician, Chennai, India
• 2010 - 2015: Bachelor in Veterinary Science and Animal Husbandry, TANUVAS, India.

Research

My project involves investigating novel tissue engineering strategies to develop 3-dimensional co-culture model of bone-tendon interface (enthesis). This is a structurally complex region with micro-gradations: tendon, uncalcified fibrocartilage, calcified fibrocartilage, and bone; with gradients in cell type, extracellular matrix (ECM) composition, collagen fiber arrangement and mechanical properties. This graded structure of the enthesis spanning 300-800 µm width dissipates stress and provides mechanical strength to withstand compression at the junction between tendon and bone. Injury to this region heals with scar tissue formation which re-ruptures. Ideally, establishing a 3D in-vitro model to study the development and regeneration of this structure can open up therapeutic options for tendon injuries.

Awards

• Principal’s career development scholarship & Edinburgh global research scholarship for pursuing PhD.
• Chief Guest Dr. A. L. Chaudhry Award for the best M.V.Sc. student in the subject of Pharmacology.

Publications

V. Prabhakaran and J.Z.Paxton. Towards scaffold-less bone production: investigating spheroid formation in rat osteoblasts. Poster presentation at TCES 2021 Virtual conference.

Vinothini P, Ramesh S, Nair SV, Preetha SP, Sriram P. Pharmacokinetics and relative bioavailability of tiamulin in broiler chicken as influenced by different routes of administration. J vet Pharmacol Therap. 2019. 42:447-451.

Amit Khatti, Vinothini P, Nitish SK, Kumar PR, Patra MK, Narayanan K, Harendra Kumar and Singh SK. Diagnostic Evaluation of Immunoassay Kits for Ealy Pregnancy Detection in Cattle. J. Anim. Res. 2021. 11(1): 25-32.

Duraisamy S, Srinivasan R, Vinothini P, Venkatesh K, Porteen, and Padmanabhan S. Pharmacokinetic Disposition and Residue Status of Tilmicosin in Broiler Chicken after ‘In-Crop’ and ‘In-Water’ Administration. Indian Journal of Animal Research (Accepted).