Cristina Martinez Gonzalez

My research combines optical tissue clearing with light-sheet microscopy to investigate models of autism spectrum disorders at the whole-brain level.

Dr Cristina Martinez Gonzalez

Post-doctoral Research Fellow

Hugh Robson Building

15 George Square

Edinburgh, EH8 9XD

Contact details


 Web: Nolan Lab Research Group

 Web: Duguid Lab Research Group


Personal profile

  • 2017-present                  Post-doctoral research fellow. Simons Initiative for the Development Brain (SIDB). University of Edinburgh.
  • 2016- 2016                       Visiting Post-doctoral fellow at Prof. Catherina Becker’s group. University of Edinburgh.
  • 2013-2016                        Post-doctoral scientist at Prof. Gregoire Courtine’s group. EPFL, Switzerland.
  • 2007-2012                         D.Phil in Neurosciences. University of Oxford, UK.
  • 2004-2006                         M.Sc. in Biochemistry. UNAM, Mexico.
  • 2000-2004                         B.Sc. in Basic biomedical research.   UNAM, Mexico.


My research combines optical tissue clearing with light-sheet microscopy to investigate rodent models of autism spectrum disorders at the whole-brain level.

Relevant Publications

Louros S.R*, Seo S.S*, Maio B, Martinez-Gonzalez C, Gonzalez-Lozano M.A, Muscas M, Verity N.C, Wills J.C, Li K.W, Nolan M.F, Osterweil E.K. Excessive proteostasis contributes to pathology in Fragile X Syndrome. In press. Neuron (2022)

Hristova K*, Martinez-Gonzalez C*, Watson TC*, Codadu NK, Hashemi K, Kind PC, Nolan MF, Gonzalez-Sulser A. Medial septal GABAergic neurons reduce seizure duration upon optogenetic closed-loop stimulation. Brain. 2021 Jun 22;144(5):1576-1589. 

Bonizzato, M., Pidpruzhnykova, G., Pavlova, N., Shkorbatova, P., Martinez-Gonzalez, C., DiGiovanna, J., Barraud, Q., Micera, S., and Courtine, G. Multi-pronged neuromodulation intervention engages the residual motor circuitry to facilitate walking in a rat model of spinal cord injury. Nat Commun 12, 1925 (2021). 

Asboth, L., Friedli, L., Beauparlant, J., Martinez-Gonzalez C, Anil, S., Rey, E., Baud, L., Pidpruzhnykova, G., Anderson, M.A.M.A., Shkorbatova, P., Batti, L., Pagès, S., Kreider, J., Schneider, B.L.B.L., Barraud, Q., & Courtine, G. (2018) Cortico–reticulo–spinal circuit reorganization enables functional recovery after severe spinal cord contusion. Nat Neurosci21, 576–588 (2018). 

Tennant, S.A., Fischer, L., Garden, D.L.F., Gerlei, K.Z., Martinez-Gonzalez, C, McClure, C., Wood, E.R., & Nolan, M.F. (2018) Stellate Cells in the Medial Entorhinal Cortex Are Required for Spatial Learning. Cell Rep. 2018 Jan 30;22(5):1313-1324. 

Martinez-Gonzalez C, Bolam JP, Mena-Segovia J. Topographical organization of the pedunculopontine nucleus. Front Neuroanat. 2011 Apr 5;5:22.  

Martinez-Gonzalez C, van Andel J, Bolam JP, Mena-Segovia J. Divergent motor projections from the pedunculopontine nucleus are differentially regulated in Parkinsonism. Brain Struct Funct. 2014 Jul;219(4):1451-62.  

Martinez-Gonzalez C, Wang, H.-L., Micklem, B.R., Bolam, J.P., & Mena-Segovia, J. (2012) Subpopulations of cholinergic, GABAergic and glutamatergic neurons in the pedunculopontine nucleus contain calcium-binding proteins and are heterogeneously distributed. Eur. J. Neurosci., 35, 723–734.